PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals

Platelet derived growth factor receptors (PDGFRs) play an important role in tumor pathogenesis, and they are frequently overexpressed in glioblastoma (GBM). Earlier we have shown a higher protein expression of PDGFR isoforms (α and β) in peritumoral-tissue derived cancer stem cells (p-CSC) than in t...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Cenciarelli, Carlo, Marei, Hany E., Felsani, Armando, Casalbore, Patrizia, Sica, Gigliola, Puglisi, Maria Ausiliatrice, Cameron, Angus J.M., Olivi, Alessandro, Mangiola, Annunziato
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288168/
https://ncbi.nlm.nih.gov/pubmed/27344175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10132
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky