Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects

Hypoadiponectinemia and adiponectin resistance are implicated in the aetiology of obesity-related cardiometabolic disorders, hence represent a potential therapeutic axis. Here we characterised the effects of in vivo electrotransfer-mediated overexpression of the adiponectin receptors, AdipoR1 or Adi...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Keshvari, Sahar, Henstridge, Darren C., Ng, Choaping, Febbraio, Mark A., Whitehead, Jonathan P.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286438/
https://ncbi.nlm.nih.gov/pubmed/28145500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41792
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