Rheumatic Heart Disease and Myxomatous Degeneration: Differences and Similarities of Valve Damage Resulting from Autoimmune Reactions and Matrix Disorganization

Autoimmune inflammatory reactions leading to rheumatic fever (RF) and rheumatic heart disease (RHD) result from untreated Streptococcus pyogenes throat infections in individuals who exhibit genetic susceptibility. Immune effector mechanisms have been described that lead to heart tissue damage culmin...

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Bibliographic Details
Published in:PLoS One
Main Authors: Martins, Carlo de Oliveira, Demarchi, Lea, Ferreira, Frederico Moraes, Pomerantzeff, Pablo Maria Alberto, Brandao, Carlos, Sampaio, Roney Orismar, Spina, Guilherme Sobreira, Kalil, Jorge, Cunha-Neto, Edecio, Guilherme, Luiza
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266332/
https://ncbi.nlm.nih.gov/pubmed/28121998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170191
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