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Quantification of spatiotemporal patterns of Ras isoform expression during development

Ras proteins are important signalling hubs frequently dysregulated in cancer and in a group of developmental disorders called Rasopathies. Three Ras genes encode four proteins that differentially contribute to these phenotypes. Using quantitative real-time PCR (qRT-PCR) we have measured the gene exp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Newlaczyl, Anna U., Coulson, Judy M., Prior, Ian A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259795/
https://ncbi.nlm.nih.gov/pubmed/28117393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41297
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