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Inverse protein folding problem: designing polymer sequences.

We consider the question of how to design proteins. How can we find "good" amino acid sequences (i) that fold to a desired "target" structure as a native conformation of lowest accessible free energy and (ii) that will not simultaneously fold to many other conformations of the sa...

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Bibliografske podrobnosti
Main Authors: Yue, K, Dill, K A
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC525653/
https://ncbi.nlm.nih.gov/pubmed/1570343
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