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Electrophysiologic effects of the I(K) (1) inhibitor PA‐6 are modulated by extracellular potassium in isolated guinea pig hearts

The pentamidine analog PA‐6 was developed as a specific inward rectifier potassium current (I(K) (1)) antagonist, because established inhibitors either lack specificity or have side effects that prohibit their use in vivo. We previously demonstrated that BaCl(2), an established I(K) (1) inhibitor, c...

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Publicado en:Physiol Rep
Main Authors: Hoeker, Gregory S., Skarsfeldt, Mark A., Jespersen, Thomas, Poelzing, Steven
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256165/
https://ncbi.nlm.nih.gov/pubmed/28087819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13120
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