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Specific Targeting of Human Integrin α(v)β(3) with (111)In-Labeled Abegrin™ in Nude Mouse Models

PURPOSE: The cell adhesion molecule integrin α(v)β(3) is an important player in the process of tumor angiogenesis and metastasis. Abegrin™, a fully humanized anti-integrin α(v)β(3) monoclonal antibody, was currently in clinical trials for cancer therapy. Herein, we labeled Abegrin™ with (111)In, eva...

詳細記述

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書誌詳細
出版年:Mol Imaging Biol
主要な著者: Liu, Zhaofei, Jia, Bing, Zhao, Huiyun, Chen, Xiaoyuan, Wang, Fan
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242344/
https://ncbi.nlm.nih.gov/pubmed/20383594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-010-0302-4
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