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Specific Targeting of Human Integrin α(v)β(3) with (111)In-Labeled Abegrin™ in Nude Mouse Models
PURPOSE: The cell adhesion molecule integrin α(v)β(3) is an important player in the process of tumor angiogenesis and metastasis. Abegrin™, a fully humanized anti-integrin α(v)β(3) monoclonal antibody, was currently in clinical trials for cancer therapy. Herein, we labeled Abegrin™ with (111)In, eva...
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| Publié dans: | Mol Imaging Biol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5242344/ https://ncbi.nlm.nih.gov/pubmed/20383594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-010-0302-4 |
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