DNA Methylation Analysis of BRD1 Promoter Regions and the Schizophrenia rs138880 Risk Allele

The bromodomain containing 1 gene, BRD1 is essential for embryogenesis and CNS development. It encodes a protein that participates in histone modifying complexes and thereby regulates the expression of a large number of genes. Genetic variants in the BRD1 locus show association with schizophrenia an...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Dyrvig, Mads, Qvist, Per, Lichota, Jacek, Larsen, Knud, Nyegaard, Mette, Børglum, Anders D., Christensen, Jane H.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240986/
https://ncbi.nlm.nih.gov/pubmed/28095495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170121
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