B cell repertoires in HLA-sensitized kidney transplant candidates undergoing desensitization therapy

BACKGROUND: Kidney transplantation is the most effective treatment for end-stage renal disease. Sensitization refers to pre-existing antibodies against human leukocyte antigen (HLA) protein and remains a major barrier to successful transplantation. Despite implementation of desensitization strategie...

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Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Beausang, John F., Fan, H. Christina, Sit, Rene, Hutchins, Maria U., Jirage, Kshama, Curtis, Rachael, Hutchins, Edward, Quake, Stephen R., Yabu, Julie M.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237299/
https://ncbi.nlm.nih.gov/pubmed/28086979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1118-7
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