MR-Guided Delivery of Hydrophilic Molecular Imaging Agents Across the Blood-Brain Barrier Through Focused Ultrasound

PURPOSE: A wide variety of hydrophilic imaging and therapeutic agents are unable to gain access to the central nervous system (CNS) due to the blood-brain barrier (BBB). In particular, unless a particular transporter exists that may transport the agent across the BBB, most agents that are larger tha...

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Bibliographic Details
Published in:Mol Imaging Biol
Main Authors: Airan, Raag D., Foss, Catherine A., Ellens, Nicholas P. K., Wang, Yuchuan, Mease, Ronnie C., Farahani, Keyvan, Pomper, Martin G.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226140/
https://ncbi.nlm.nih.gov/pubmed/27481359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-016-0985-2
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