Trimethoprim-Sulfamethoxazole Prophylaxis During Live Malaria Sporozoite Immunization Induces Long-Lived, Homologous, and Heterologous Protective Immunity Against Sporozoite Challenge

Trimethoprim-sulfamethoxazole (TMP-SMX) is widely used in malaria-endemic areas in human immunodeficiency virus (HIV)–infected children and HIV-uninfected, HIV-exposed children as opportunistic infection prophylaxis. Despite the known effects that TMP-SMX has in reducing clinical malaria, its impact...

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Bibliographic Details
Published in:J Infect Dis
Main Authors: Hobbs, Charlotte V., Anderson, Charles, Neal, Jillian, Sahu, Tejram, Conteh, Solomon, Voza, Tatiana, Langhorne, Jean, Borkowsky, William, Duffy, Patrick E.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225250/
https://ncbi.nlm.nih.gov/pubmed/28077589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw482
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