Potential inhibition of HIV-1 encapsidation by oligoribonucleotide–dendrimer nanoparticle complexes

BACKGROUND: Encapsidation, the process during which the genomic RNA of HIV is packaged into viral particles, is an attractive target for antiviral therapy. This study explores a novel nanotechnology-based strategy to inhibit HIV encapsidation by an RNA decoy mechanism. The design of the 16-mer oligo...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Parboosing, Raveen, Chonco, Louis, de la Mata, Francisco Javier, Govender, Thavendran, Maguire, Glenn EM, Kruger, Hendrik G
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221794/
https://ncbi.nlm.nih.gov/pubmed/28115849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S114446
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