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Structural identifiability of equilibrium ligand-binding parameters

Understanding the interactions of proteins with their ligands requires knowledge of molecular properties, such as binding site affinities and the effects that binding at one site exerts on binding at other sites (cooperativity). These properties cannot be measured directly and are usually estimated...

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Bibliografiska uppgifter
I publikationen:J Gen Physiol
Huvudupphovsmän: Middendorf, Thomas R., Aldrich, Richard W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217090/
https://ncbi.nlm.nih.gov/pubmed/27993952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611702
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