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Structural identifiability of equilibrium ligand-binding parameters

Understanding the interactions of proteins with their ligands requires knowledge of molecular properties, such as binding site affinities and the effects that binding at one site exerts on binding at other sites (cooperativity). These properties cannot be measured directly and are usually estimated...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Middendorf, Thomas R., Aldrich, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217090/
https://ncbi.nlm.nih.gov/pubmed/27993952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611702
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