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Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3

Increasing evidence suggests that the tumor microenvironment plays a key role in the development of drug resistant tumor cells. In this study, we tried to determine whether the mesenchymal stem cells (MSCs) in the tumor microenvironment contribute to the increased chemoresistance of osteosarcoma. We...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tu, Bing, Zhu, Jing, Liu, Shen, Wang, Lei, Fan, Qiming, Hao, Yongqiang, Fan, Cunyi, Tang, Ting-Ting
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217018/
https://ncbi.nlm.nih.gov/pubmed/27340780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10219
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