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Attenuation of Compulsive-Like Behavior Through Positive Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors in Non-Induced Compulsive-Like Mice

Nicotinic α4β2 receptors are the most abundant subtypes of nicotinic acetylcholine receptors (nAChRs) expressed in brain regions implicated in obsessive compulsive disorder (OCD). These receptors are known to modify normal and addictive behaviors by modulating neuronal excitability. Desformylflustra...

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Bibliographische Detailangaben
Veröffentlicht in:Front Behav Neurosci
Hauptverfasser: Mitra, Swarup, Mucha, Mckenzie, Khatri, Shailesh N., Glenon, Richard, Schulte, Marvin K., Bult-Ito, Abel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214813/
https://ncbi.nlm.nih.gov/pubmed/28105008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2016.00244
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