Autoregulated expression of p53 from an adenoviral vector confers superior tumor inhibition in a model of prostate carcinoma gene therapy

Alternative treatments for cancer using gene therapy approaches have shown promising results and some have even reached the marketplace. Even so, additional improvements are needed, such as employing a strategically chosen promoter to drive expression of the transgene in the target cell. Previously,...

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Bibliographic Details
Published in:Cancer Biol Ther
Main Authors: Tamura, Rodrigo Esaki, da Silva Soares, Rafael Bento, Costanzi-Strauss, Eugenia, Strauss, Bryan E.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199163/
https://ncbi.nlm.nih.gov/pubmed/27646031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1235655
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