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Tetrahydrofurobenzofuran cymserine, a potent butyrylcholinesterase inhibitor and experimental Alzheimer drug candidate, enzyme kinetic analysis

Synaptic loss, particularly related to the forebrain cholinergic system, is considered to be an early event that leads to Alzheimer’s disease (AD) and has led to the development of acetylcholinesterase inhibitors (AChE-Is) as the mainstay of treatment for several degenerative disorders that culminat...

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Detalhes bibliográficos
Publicado no:J Neural Transm (Vienna)
Main Authors: Kamal, Mohammad A., Qu, Xianqin, Yu, Qian sheng, Tweedie, David, Holloway, Harold W., Li, Yazhou, Tan, Yi, Greig, Nigel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193500/
https://ncbi.nlm.nih.gov/pubmed/18235987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-008-0022-y
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