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Total Synthesis of the Complete Protective Antigen of Vibrio cholerae O139
The first chemical synthesis of the complete protective O-antigen of a human disease-causing pathogenic bacterium is described. The synthesis involved a protecting group strategy which facilitated regioselectivity of the key transformations, stereoselective glycosylations, and allowed one-step globa...
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| Published in: | Angew Chem Int Ed Engl |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5165651/ https://ncbi.nlm.nih.gov/pubmed/27623688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201606116 |
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