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Modeling intratumor heterogeneity through CRISPR-barcodes

We have devised a barcoding strategy to recapitulate cancer evolution through the emergence of subclonal mutations of interest, whose effects can be monitored in a dynamic manner. This approach can be easily adapted for a variety of applications, including combined modeling of multiple mechanisms of...

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Bibliografiska uppgifter
I publikationen:Mol Cell Oncol
Huvudupphovsmän: Guernet, Alexis, Aaronson, Stuart A., Anouar, Youssef, Grumolato, Luca
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5160400/
https://ncbi.nlm.nih.gov/pubmed/28090577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1227894
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