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The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation.

The mechanism of Tat transactivation was studied by treating cell lines containing Tat-defective viruses with purified Tat protein. These cell lines constitutively produce very low levels of virus in the absence of Tat, as measured by p24 antigen levels. Virus production can be increased greater tha...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Feinberg, M B, Baltimore, D, Frankel, A D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1991
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC51590/
https://ncbi.nlm.nih.gov/pubmed/2023953
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