Structural implications of Ca(2+)-dependent actin-bundling function of human EFhd2/Swiprosin-1

EFhd2/Swiprosin-1 is a cytoskeletal Ca(2+)-binding protein implicated in Ca(2+)-dependent cell spreading and migration in epithelial cells. EFhd2 domain architecture includes an N-terminal disordered region, a PxxP motif, two EF-hands, a ligand mimic helix and a C-terminal coiled-coil domain. We rep...

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Pubblicato in:Sci Rep
Autori principali: Park, Kyoung Ryoung, Kwon, Min-Sung, An, Jun Yop, Lee, Jung-Gyu, Youn, Hyung-Seop, Lee, Youngjin, Kang, Jung Youn, Kim, Tae Gyun, Lim, Jia Jia, Park, Jeong Soon, Lee, Sung Haeng, Song, Woo Keun, Cheong, Hae-Kap, Jun, Chang-Duk, Eom, Soo Hyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156911/
https://ncbi.nlm.nih.gov/pubmed/27974828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39095
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