Relationship between APOE Genotype and Structural MRI Measures throughout Adulthood in the Study of Health in Pomerania Population-Based Cohort

BACKGROUND AND PURPOSE: The presence of the apolipoprotein E ε4 allele is the strongest sporadic Alzheimer disease genetic risk factor. We hypothesized that apolipoprotein E ε4 carriers and noncarriers may already differ in imaging patterns in midlife. We therefore sought to identify the effect of a...

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Vydáno v:AJNR Am J Neuroradiol
Hlavní autoři: Habes, M., Toledo, J.B., Resnick, S.M., Doshi, J., Van der Auwera, S., Erus, G., Janowitz, D., Hegenscheid, K., Homuth, G., Völzke, H., Hoffmann, W., Grabe, H.J., Davatzikos, C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Neuroradiology 2016
Témata:
Adult Brain
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154957/
https://ncbi.nlm.nih.gov/pubmed/27173368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3174/ajnr.A4805
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