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Genetically Heterogeneous Mice Show Age-related Vision Deficits Not Related to Increased Rod Cell L-type Calcium Channel Function In Vivo
Visual performance declines over time in humans and 2-18 mo outbred Long-Evans (LE) rats; vision is maintained in inbred 2- 18 mo C57BL/6 (B6) mice. Increased rod L-type calcium channel (LTCC) function predicts visual decline in LE rats but does not occur in B6 mice. Genetic diversity may contribute...
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| Udgivet i: | Neurobiol Aging |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5154834/ https://ncbi.nlm.nih.gov/pubmed/27823846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.09.009 |
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