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Genetically Heterogeneous Mice Show Age-related Vision Deficits Not Related to Increased Rod Cell L-type Calcium Channel Function In Vivo

Visual performance declines over time in humans and 2-18 mo outbred Long-Evans (LE) rats; vision is maintained in inbred 2- 18 mo C57BL/6 (B6) mice. Increased rod L-type calcium channel (LTCC) function predicts visual decline in LE rats but does not occur in B6 mice. Genetic diversity may contribute...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Berkowitz, Bruce A., Miller, Richard A., Roberts, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154834/
https://ncbi.nlm.nih.gov/pubmed/27823846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.09.009
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