SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis

Actin plays a critical role during the early stages of pathogenic microbe internalization by immune cells. In this study, we identified a key mechanism of actin filament tethering and stabilization to the surface of phagosomes in human dendritic cells. We found that the actin-binding protein SWAP70...

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Udgivet i:Cell Rep
Main Authors: Baranov, Maksim V., Revelo, Natalia H., Dingjan, Ilse, Maraspini, Riccardo, ter Beest, Martin, Honigmann, Alf, van den Bogaart, Geert
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149533/
https://ncbi.nlm.nih.gov/pubmed/27806292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.021
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