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Identification of a GUAAY pentaloop sequence involved in a novel RNA loop-helix interaction

Large RNAs often utilize GNRA tetraloops as structural elements to stabilize the overall tertiary fold. These tetraloop-receptor (TR) interactions have a conserved geometry in which the tetraloop docks into the receptor at an angle of ~15 degrees from the helix containing the receptor. Here we show...

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Pubblicato in:J Mol Biol
Autori principali: Chan, Russell T., Keating, Kevin S., Go, Michaela C., Toor, Navtej
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138090/
https://ncbi.nlm.nih.gov/pubmed/27771480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.10.015
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