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Predicting the recurrence of noncoding regulatory mutations in cancer

BACKGROUND: One of the greatest challenges in cancer genomics is to distinguish driver mutations from passenger mutations. Whereas recurrence is a hallmark of driver mutations, it is difficult to observe recurring noncoding mutations owing to a limited amount of whole-genome sequenced samples. Hence...

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書目詳細資料
發表在:BMC Bioinformatics
Main Authors: Yang, Woojin, Bang, Hyoeun, Jang, Kiwon, Sung, Min Kyung, Choi, Jung Kyoon
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135808/
https://ncbi.nlm.nih.gov/pubmed/27912731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1385-y
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