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Predicting the recurrence of noncoding regulatory mutations in cancer

BACKGROUND: One of the greatest challenges in cancer genomics is to distinguish driver mutations from passenger mutations. Whereas recurrence is a hallmark of driver mutations, it is difficult to observe recurring noncoding mutations owing to a limited amount of whole-genome sequenced samples. Hence...

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Bibliografski detalji
Izdano u:BMC Bioinformatics
Glavni autori: Yang, Woojin, Bang, Hyoeun, Jang, Kiwon, Sung, Min Kyung, Choi, Jung Kyoon
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135808/
https://ncbi.nlm.nih.gov/pubmed/27912731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1385-y
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