Mechanism of hard nanomaterial clearance by the liver

The liver and spleen are major biological barriers to translating nanomedicines because they sequester the majority of administered nanomaterials and prevent delivery to diseased tissue. Here we examined the blood clearance mechanism of administered hard nanomaterials in relation to blood flow dynam...

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Pubblicato in:Nat Mater
Autori principali: Tsoi, Kim M., MacParland, Sonya A., Ma, Xue-Zhong, Spetzler, Vinzent N., Echeverri, Juan, Ouyang, Ben, Fadel, Saleh M., Sykes, Edward A., Goldaracena, Nicolas, Kaths, Johann M., Conneely, John B., Alman, Benjamin A., Selzner, Markus, Ostrowski, Mario A., Adeyi, Oyedele A., Zilman, Anton, McGilvray, Ian D., Chan, Warren C.W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132626/
https://ncbi.nlm.nih.gov/pubmed/27525571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4718
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