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Memantine Effects On Sensorimotor Gating and Mismatch Negativity in Patients with Chronic Psychosis

Patients with chronic psychotic disorders (CPD) exhibit deficient sensorimotor gating (measured by prepulse inhibition (PPI) of startle) and mismatch negativity (MMN). In healthy subjects (HS), N-methyl-D-aspartate (NMDA) antagonists like memantine and ketamine increase PPI, and under some condition...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Swerdlow, Neal R, Bhakta, Savita, Chou, Hsun-Hua, Talledo, Jo A, Balvaneda, Bryan, Light, Gregory A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130118/
https://ncbi.nlm.nih.gov/pubmed/26062785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.162
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