CTLA4 as Immunological Checkpoint in the Development of Multiple Sclerosis

We investigated a patient who developed multiple sclerosis (MS) during treatment with the CTLA4‐blocking antibody ipilimumab for metastatic melanoma. Initially he showed subclinical magnetic resonance imaging (MRI) changes (radiologically isolated syndrome). Two courses of ipilimumab were each follo...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Gerdes, Lisa Ann, Held, Kathrin, Beltrán, Eduardo, Berking, Carola, Prinz, Jörg C., Junker, Andreas, Tietze, Julia K., Ertl‐Wagner, Birgit, Straube, Andreas, Kümpfel, Tania, Dornmair, Klaus, Hohlfeld, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129566/
https://ncbi.nlm.nih.gov/pubmed/27351142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24715
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