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Marine Fungi as Producers of Benzocoumarins, a New Class of Inhibitors of Glycogen-Synthase-Kinase 3β

The glycogen-synthase-kinase 3 (GSK-3) is an important target in drug discovery. This enzyme is involved in the signaling pathways of type 2 diabetes, neurological disorders, cancer, and other diseases. Therefore, inhibitors of GSK-3 are promising drug candidates for the treatment of a broad range o...

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Bibliographic Details
Published in:Mar Drugs
Main Authors: Wiese, Jutta, Imhoff, Johannes F., Gulder, Tobias A. M., Labes, Antje, Schmaljohann, Rolf
Format: Artigo
Language:Inglês
Published: MDPI 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5128743/
https://ncbi.nlm.nih.gov/pubmed/27801816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14110200
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