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Product release is rate-limiting for catalytic processing by the Dengue virus protease
Dengue Virus (DENV) is the most prevalent global arbovirus, yet despite an increasing burden to health care there are currently no therapeutics available to treat infection. A potential target for antiviral drugs is the two-component viral protease NS2B-NS3pro, which is essential for viral replicati...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5126634/ https://ncbi.nlm.nih.gov/pubmed/27897196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37539 |
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