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Effect of Serotonin Transporter 5HTTLPR Polymorphism on Gastrointestinal Intolerance to Metformin: A GoDARTS Study

OBJECTIVE: The mechanism causing gastrointestinal intolerance to metformin treatment is unknown. We have previously shown that reduced-function alleles of organic cation transporter 1 (OCT1) are associated with increased intolerance to metformin. Considering recent findings that serotonin transporte...

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Publicat a:Diabetes Care
Autors principals: Dujic, Tanja, Zhou, Kaixin, Tavendale, Roger, Palmer, Colin N.A., Pearson, Ewan R.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122449/
https://ncbi.nlm.nih.gov/pubmed/27493135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc16-0706
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