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Impact of CYP2C19 Variants on Clinical Efficacy of Clopidogrel and 1-Year Clinical Outcomes in Coronary Heart Patients Undergoing Percutaneous Coronary Intervention

The impact of pharmacogenetic variants of cytochrome P450 2C19 (CYP2C19) on clopidogrel-mediated effects on platelet inhibition, inflammatory response and endothelial function, as well as risk of major adverse cardiovascular events (MACE), in coronary heart patients undergoing percutaneous coronary...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Sun, Hong, Qu, Qiang, Chen, Zhen-Fan, Tan, Sheng-Lan, Zhou, Hai-Jun, Qu, Jian, Chen, Hui
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121225/
https://ncbi.nlm.nih.gov/pubmed/27932982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00453
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