DNA METHYLATION BY DNMT1 AND DNMT3b METHYLTRANSFERASES IS DRIVEN BY THE MUC1-C ONCOPROTEIN IN HUMAN CARCINOMA CELLS

Aberrant expression of the DNA methyltransferases (DNMTs) and disruption of DNA methylation patterns are associated with carcinogenesis and cancer cell survival. The oncogenic MUC1-C protein is aberrantly overexpressed in diverse carcinomas; however, there is no known link between MUC1-C and DNA met...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Rajabi, Hasan, Tagde, Ashujit, Alam, Maroof, Bouillez, Audrey, Pitroda, Sean, Suzuki, Yozo, Kufe, Donald
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121097/
https://ncbi.nlm.nih.gov/pubmed/27212035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.180
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