Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth

Binding of the transcriptional co-activator YAP with the transcription factor TEAD stimulates growth of the heart and other organs. YAP overexpression potently stimulates fetal cardiomyocyte (CM) proliferation, but YAP's mitogenic potency declines post-natally. While investigating factors that...

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Veröffentlicht in:Dev Cell
Hauptverfasser: Lin, Zhiqiang, Guo, Haidong, Cao, Yuan, Zohrabian, Sylvia, Zhou, Pingzhu, Ma, Qing, VanDusen, Nathan, Guo, Yuxuan, Zhang, Jin, Stevens, Sean M., Liang, Feng, Quan, Qimin, van Gorp, Pim R., Li, Amy, dos Remedios, Cristobal, He, Aibin, Bezzerides, Vassilios J., Pu, William T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121000/
https://ncbi.nlm.nih.gov/pubmed/27720608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.09.005
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