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HMGA2 Moderately Increases Fetal Hemoglobin Expression in Human Adult Erythroblasts
Induction of fetal hemoglobin (HbF) has therapeutic importance for patients with beta-hemoglobin disorders. Previous studies showed that let-7 microRNAs (miRNAs) are highly regulated in erythroid cells during the fetal-to-adult developmental transition, and that targeting let-7 mediated the up-regul...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5115839/ https://ncbi.nlm.nih.gov/pubmed/27861570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166928 |
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