Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas

RNA polymerase II mediates the transcription of all protein-coding genes in eukaryotic cells, a process that is fundamental to life. Genomic mutations altering this enzyme have not previously been linked to any pathology in humans, which is a testament to its indispensable role in cell biology. On t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Genet
मुख्य लेखकों: Clark, Victoria E, Harmancı, Akdes Serin, Bai, Hanwen, Youngblood, Mark W, Lee, Tong Ihn, Baranoski, Jacob F, Ercan-Sencicek, A Gulhan, Abraham, Brian J, Weintraub, Abraham S, Hnisz, Denes, Simon, Matthias, Krischek, Boris, Erson-Omay, E Zeynep, Henegariu, Octavian, Carrión-Grant, Geneive, Mishra-Gorur, Ketu, Durán, Daniel, Goldmann, Johanna E, Schramm, Johannes, Goldbrunner, Roland, Piepmeier, Joseph M, Vortmeyer, Alexander O, Günel, Jennifer Moliterno, Bilgüvar, Kaya, Yasuno, Katsuhito, Young, Richard A, Günel, Murat
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114141/
https://ncbi.nlm.nih.gov/pubmed/27548314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3651
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन