Systemic Radical Scavenger Treatment of a Mouse Model of Rett Syndrome: Merits and Limitations of the Vitamin E Derivative Trolox

Rett syndrome (RTT) is a severe neurodevelopmental disorder typically arising from spontaneous mutations in the X-chromosomal methyl-CpG binding protein 2 (MECP2) gene. The almost exclusively female Rett patients show an apparently normal development during their first 6–18 months of life. Subsequen...

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Foilsithe in:Front Cell Neurosci
Main Authors: Janc, Oliwia A., Hüser, Marc A., Dietrich, Katharina, Kempkes, Belinda, Menzfeld, Christiane, Hülsmann, Swen, Müller, Michael
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2016
Ábhair:
Neuroscience
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109403/
https://ncbi.nlm.nih.gov/pubmed/27895554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00266
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