Thymol and eugenol derivatives as potential antileishmanial agents

In Northeastern Brazil visceral leishmaniasis is endemic with lethal cases among humans and dogs. Treatment is toxic and 5–10% of humans die despite treatment. The aim of this work was to survey natural active compounds to find new molecules with high activity and low toxicity against Leishmania inf...

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Bibliografski detalji
Izdano u:Bioorg Med Chem
Glavni autori: de Morais, Selene Maia, Vila-Nova, Nadja Soares, Bevilaqua, Claudia Maria Leal, Rondon, Fernanda Cristina, Lobo, Carlos Henrique, de Alencar Araripe Noronha Moura, Arlindo, Sales, Antônia Débora, Rodrigues, Ana Paula Ribeiro, de Figuereido, José Ricardo, Campello, Claudio Cabral, Wilson, Mary E., de Andrade, Heitor Franco
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106290/
https://ncbi.nlm.nih.gov/pubmed/25281268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.08.020
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