Thymol and eugenol derivatives as potential antileishmanial agents

In Northeastern Brazil visceral leishmaniasis is endemic with lethal cases among humans and dogs. Treatment is toxic and 5–10% of humans die despite treatment. The aim of this work was to survey natural active compounds to find new molecules with high activity and low toxicity against Leishmania inf...

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Publicado en:Bioorg Med Chem
Main Authors: de Morais, Selene Maia, Vila-Nova, Nadja Soares, Bevilaqua, Claudia Maria Leal, Rondon, Fernanda Cristina, Lobo, Carlos Henrique, de Alencar Araripe Noronha Moura, Arlindo, Sales, Antônia Débora, Rodrigues, Ana Paula Ribeiro, de Figuereido, José Ricardo, Campello, Claudio Cabral, Wilson, Mary E., de Andrade, Heitor Franco
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106290/
https://ncbi.nlm.nih.gov/pubmed/25281268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.08.020
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