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Conformational study on cyclic melanocortin ligands and new insight into their binding mode at the MC4 receptor
The melanocortin receptors are involved in many physiological functions, including pigmentation, sexual function, feeding behavior, and energy homeostasis, making them potential targets to treat obesity, sexual dysfunction, etc. Understanding the basis of the ligand-receptor interactions is crucial...
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| Pubblicato in: | Eur J Med Chem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5102844/ https://ncbi.nlm.nih.gov/pubmed/21652123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.05.038 |
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