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Ascorbic acid oxidation of thiol groups from dithiotreitol is mediated by its conversion to dehydroascorbic acid

The aim of the present study was to investigate whether the in vitro pro-oxidant effect of ascorbic acid towards thiol groups could be mediated by free radicals formed during its auto-oxidation and/or by a direct oxidation of -SH groups by its oxidized form (dehydroascorbic acid). This hypothesis wa...

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Bibliografiske detaljer
Udgivet i:EXCLI J
Main Authors: Barbosa, Nilda B.V., Lissner, Leandro A., Klimaczewski, Cláudia V., Colpo, Elisangela, Rocha, Joao B.T.
Format: Artigo
Sprog:Inglês
Udgivet: Leibniz Research Centre for Working Environment and Human Factors 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099875/
https://ncbi.nlm.nih.gov/pubmed/27847448
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