Donor and recipient genetic variants in NLRP3 associate with early acute rejection following kidney transplantation

NLRP3 (NOD-like receptor family, pyrin domain containing 3) is a member of the inflammasome family and is of special interest in renal disease. Experimental studies have shown that Nlrp3 plays a significant role in the induction of renal damage and dysfunction in acute and chronic renal injury. Howe...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Dessing, Mark C., Kers, Jesper, Damman, Jeffrey, Navis, Gerjan J., Florquin, Sandrine, Leemans, Jaklien C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098240/
https://ncbi.nlm.nih.gov/pubmed/27819323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36315
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