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An Ancient Fecundability-Associated Polymorphism Switches a Repressor into an Enhancer of Endometrial TAP2 Expression

Variation in female reproductive traits, such as fertility, fecundity, and fecundability, is heritable in humans, but identifying and functionally characterizing genetic variants associated with these traits has been challenging. Here, we explore the functional significance and evolutionary history...

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Библиографические подробности
Опубликовано в: :Am J Hum Genet
Главные авторы: Mika, Katelyn M., Lynch, Vincent J.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097936/
https://ncbi.nlm.nih.gov/pubmed/27745831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.09.002
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