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An Ancient Fecundability-Associated Polymorphism Switches a Repressor into an Enhancer of Endometrial TAP2 Expression

Variation in female reproductive traits, such as fertility, fecundity, and fecundability, is heritable in humans, but identifying and functionally characterizing genetic variants associated with these traits has been challenging. Here, we explore the functional significance and evolutionary history...

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Bibliografische gegevens
Gepubliceerd in:Am J Hum Genet
Hoofdauteurs: Mika, Katelyn M., Lynch, Vincent J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097936/
https://ncbi.nlm.nih.gov/pubmed/27745831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.09.002
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