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Neonatal disease environment limits the efficacy of retinal transplantation in the LCA8 mouse model

BACKGROUND: Mutations of Crb1 gene cause irreversible and incurable visual impairment in humans. This study aims to use an LCA8-like mouse model to identify host-mediated responses that might interfere with survival, retinal integration and differentiation of grafted cells during neonatal cell thera...

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Vydáno v:BMC Ophthalmol
Hlavní autoři: Cho, Seo-Hee, Song, Ji Yun, Shin, Jinyeon, Kim, Seonhee
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095973/
https://ncbi.nlm.nih.gov/pubmed/27809828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-016-0368-0
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